Optic neuritis is an uncommon condition in the pediatric population and usually underlies a viral cause. Optic neuritis, its differential diagnosis and management. Experiencia clinica en anos optic neuritis in children. Although the visual prognosis is excellent in the majority of cases, many patients develop pathology, such as. However, the rate of conversion to ms after optic neuritis in children based upon brain mri findings is unknown. Pediatric optic neuritis may present as a clinically isolated syndrome or in the setting of underlying neurologic disease.
Optic neuritis on occurs in approximately onefourth of children presenting with an initial demyelinating event. Optic neuritis is a demyelinating inflammation of the optic nerve. Neuritis optica diagnostico y tratamiento mayo clinic. It is also known as optic papillitis when the head of the optic nerve is involved, neuroretinitis when there is a combined involvement of optic disc and surrounding retina in the macular area and retrobulbar neuritis when the. As established by the optic neuritis treatment trial, an abnormal baseline brain mri is a strong predictor of ms after isolated optic neuritis in adults. As established by the optic neuritis treatment trial, an abnormal baseline brain mri is a strong predictor of ms after. The ocular symptoms of nmo include optic neuritis, vision loss and unilateral or bilateral ocular pain. In the united states, optic neuritis occurs more commonly in caucasians than in africanamericans. The treatment of optic neuritis requires first that the physician determine the etiology and comorbidities of the affected patient in order to plan a proper therapeutic plan. Apr 10, 2018 o ptic neuritis is defined as an inflammatory disease of the optic nerve. Neuropatia optica isquemica anterior genetic and rare. Neuropatia optica inflamatoria recurrente cronica crion.
Optic neuritis is often the initial presentation of multiple sclerosis ms. Though this disease is more common in adults, the pediatric ophthalmologist should also be aware of it, as well as its evaluation and treatment, because associations between optic neuritis and other neuroinflammatory syndromes may affect final visual and systemic outcomes. Optic neuritis on is defined as inflammation of the optic nerve, which is mostly idiopathic. Neuropatia optica isquemica disturbios oftalmologicos. Acute optic neuritis is the most common optic neuropathy affecting young adults.
O ptic neuritis is defined as an inflammatory disease of the optic nerve. This condition, also known as devic disease, is an autoimmune disorder characterized by optic neuritis and myelitis that spares the brain in early stages. Significant clinical investigation of optic neuritis occurring in adults guides current clinical practices. Exciting developments have occurred over the past decade in understanding of optic neuritis pathophysiology, and these developments have been translated into treatment trials. Optic neuritis may be related to specific infections, diseases of the adjacent sinuses or orbital structures. In pediatric optic neuritis usually occurs after an infectious event, with papilledema, bilateral and with good prognosis, with a low incidence of conversion to multiple sclerosis. Efns guidelines on diagnosis and management of neuromyelitis. In pediatric optic neuritis usually occurs after an infectious event, with. Neurologic impairment 10 years after optic neuritis. Aug 30, 2016 optic neuritis on occurs in approximately onefourth of children presenting with an initial demyelinating event. In its typical form, optic neuritis presents as an inflammatory demyelinating disorder of the optic nerve, which can be associated with. In the past decade, the disease phenotypes for demyelinating syndromes in children have been more clearly defined. Jun 18, 2019 less commonly, pediatric optic neuritis may be the first manifestation of multiple sclerosis ms or part of a more diffuse demyelinating disorder, including acute disseminated encephalomyelitis or neuromyelitis optica devic disease. The risk of evolving multiple sclerosis is probably less than in adults, but pediatric optic neuritis is more likely to be an initial manifestation of acute disseminated encephalomyelitis.
Eye practitioners should be also aware of neuromyelitis optica nmo. Our neuropaediatrics department has assessed 20,744 patients in the last 27 years, of whom 14 were diagnosed with on. Optic neuritis is a condition that can happen because of a disease or without any specific known cause. The aim of this paper is to present the clinical and laboratory characteristics of cases of optic neuritis in children. Steroids may hasten visual recovery, but they do not change visual outcome except in cases because of neuromyelitis optica. Retrospective analysis of all patients younger than 16 years old, with clinical criteria of optic neuritis were revised at the pediatric neurology department of the hospital universitario dr. Differences in presentation and prognosis exist for pediatric patients with optic neuritis when compared with adults including the risk of developing multiple sclerosis. Abstract inflammatory optic neuritis on is the most frequent cause of acute visual loss in young adults.